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Pyrrolizidine is a nitrogen-containing heterocyclic compound that forms the structural core of pyrrolizidine alkaloids (PAs), which are commonly found in various plant species and are known for their hepatotoxic (liver-damaging) effects. In contrast, nicotine—a naturally occurring alkaloid in tobacco plants (Nicotiana tabacum)—is derived from the related structures of pyridine and pyrrolidine.
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